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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ccd5b2d4a21268a9ae94d4bd9941f1a46666ff701889b1922fc0994f7a019cc2' 
  AND token = '8nYQ+eC/8YFNA1ILZgluRAx+5C7g6P+GCExxc/Ea6MQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}