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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a45cd6516e9c531898cc328ab334c4264f4f11cdb7ba40a297afe20189526f44' 
  AND token = 'IC7QqnhU8ROEdUC00UnqUxcyHSz9WxoHQUjTcZ4vSrI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}