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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45a8bce8262ef0788f0a2eb31e3ddbaa8ecc96edd063cdf92ba087da6fc12ce4' 
  AND token = 'IPALD6nFWD9hjLjMuut7bNdFGRnz5/CI+zSaSavmMVM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}