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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f22fc8ecbf4c2d4dad0be53cfa99fad65b64c18464f62ee12b6f3df277ddaea' 
  AND token = '9McqAPLoxyuUYdbrppbiNRL7lXvgmdi7rXCmMAGXots=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}