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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b38c8e6db9208110c597c29463bd469e6fddeced822f9b04a6c5dac70239ff8a' 
  AND token = 'yupMBMTB4DOrQtdd/kZhRpy5XcseJW8rZ+Kp1iVbkfo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}