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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '734b6380a62ff29b360755c879af57e84475b8a1bf68d2efe8e7176ceacb8014' 
  AND token = 'HgmCU17r98oGEPzRRHcf47dcNmsvJ0KCdUyPFFLDF5Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}