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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9cca61f3ff54b8281b34baee8331f8633e68897ab19e68dc8e00b1b3295c8278' 
  AND token = 'jP2oVWtrm3wg2fMCpU2kEU8PZoL2Z7fMTlzq9irdNJI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}