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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '24ce1f0b9f00f2c01cb37187c903596ff8817af1e420f81994e116c13abf4c1d' 
  AND token = 'VtUMR95t5dCUzyTmAyH7hV7KmI5x42BSXCoh0uHVQtI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}