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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '03e0c6a1d607c0973c9956b8641cc19c34bfda73a18dab27b786545b4f83bbcb' 
  AND token = 'KeLcvLyp0DU09N7IRKVSIMiAnvEhzFhfLXcK4cYSiws=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}