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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75c817b6ebc69aef9611a4c7099aac03eb99d2702f747cb97ee3eb768613e350' 
  AND token = 't41MFxco0ku5IHrfU+rLps1xqH72B+R5/JfmO0Gq91w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}