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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f52d01d12e0bbf830cb68f883962f82fc5c3b08152e76d12dca2817726ce7cae' 
  AND token = 'l8NMGelQHjuTiR2ONQGNYc1Dcpb9woVa1W8x+mF0bfQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}