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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f33fe2a6c55cd288727b70370c130c4eab346be42f25eec974d84808d2dc9d8' 
  AND token = '5JA2JWFu6tT+NYD9OwQG2NQM5V9RnZPnSDyPEOEUV2I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}