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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6b5fce80ed491e41e67cfd00446065c9d5914508c591523f6f51a24f9388158' 
  AND token = 'uiR53f+Dh/RwFbI5pW5w+fOxJk22zJaR6Hx48qBPQCQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}