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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af528b1184a9fe1c82f108c6dd350f65ca23161f7b159cd29c0d3725e496c5e1' 
  AND token = 'Y4A6uFs7Z8Kxh9MVvtdNJRk1umbktvEthmyOCEKlvNI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}