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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e21a66b8e8abf40d5e993e08d9e262c8a247478678ec60ea7ea4fba3dee0b639' 
  AND token = 'kYqpDIAwxC1eP7rKHvmRvA5+cX2NdkzMoIZwh9ejB5M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}