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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1c365dfbfa3e4779457fe55cdbaffe16e41099f4859ac0b8c540495ed45366f' 
  AND token = 'SA8Yp8RqIyVi8T2r7E2/3gNqVmsXOEI8d7yuQiRFfCs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}