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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0fda0a3044a3fa95aa866b60cf4c1acf6687ca1c2d50c06b9acc947c3a97850' 
  AND token = '37awLz5osLEALliHpUhPptMRfvHqI0avI0VGCDiiEcI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}