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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45747d4c2b9262880e94da87601d0ebdc8630921dae65a9a6bffff72ac22f982' 
  AND token = '8wm2XREQNQT1koyNrxhcIU/2Wd5CkIZ0cR6A9Kxe0yo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}