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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '34c7e07b5871f9ff473d017ac67bc548b184029f2f2a334a119bbe9da71e8963' 
  AND token = 'J+b+AcYZmDmkAW9zyEOhcNpoYVZteAR5Iv29ARRBt8g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}