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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65b94ad03de8dfdf50d5ecd7fc543bd78ba7fcd187d1e062171ca1f57558b169' 
  AND token = 'tXZ48a6jyYWFX7Iq39HJKFdBaStFQ+nyffmZENmBRIo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}