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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8920fbeb95f596af3626097a5253deb786f48fb8c19576ac6632ad187ab16a53' 
  AND token = 'yVTxIoOQIydzs62Qz7aqxfPnWO9ziKGaup1xaa+TsD8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}