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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '814c03ec798038ba2b650e675572980e90bf817b8ece123c3f039e998667253a' 
  AND token = 'AZTQjbbOfRbP4F7QgCqwJY0W40BSbEDvke+9Pvl/6Ks=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}