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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e110d65359b08ee602f0018e40b6c80c1cf7eb0d6fa126f8522462d66c95b1d5' 
  AND token = 'bxnlJ1q2YJCoSLp7oo8isKca6qdCJ2SOFZf2406ETG0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}