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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18e8256577ffdd7f88b1ce82675ea34b11ff5c029b5fe5aeb29e778af997c551' 
  AND token = 'rdxm/BrDdwFNDbl+OCeUoLJ5TETsiOmsAp2mcUGMKA4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}