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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '766f4d3ae860ed5f1d8f9ed7d29d12723cf81999ecd26298da031bfd2b2b0ca7' 
  AND token = 'ZPEo7KJRU5nfbOTgE3L/2w9dtTYsZYGmtAr3UtDpf5Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}