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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0cc5d99bae175d42fc508a2f6eafa1d35e331be604e79e555aeb74dde8c784ab' 
  AND token = '9Fa9MQZDpPx/ekdgz7pQ35QDc3xMVjZxWX9vyXVZeVQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}