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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25731f8aeb34cb832f720215ca8aeca9498195a66ff3024ea0719512995dad13' 
  AND token = '2yMO3WTYC8nnu0JylWJh3aLKsW3xHUaQT+WbNwaTyhw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}