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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '92f188e51133c33884d1cf1dc548d1cdcdc698e89cb4009eaddd5af91eb97aa8' 
  AND token = 'aFI5YAbnPhEIR9IdDjDVbHfbypeeIdzvWRm+oMnGxyE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}