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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a25d45b1f9b39b499cc847a77ef14a9f9860631128636812037e18417d16a83' 
  AND token = 'eaXwqnjgX50/i/y+/fwNVJDdnDd9MXoxiXdUurjrNfc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}