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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48479a4c7d5dcecb8600e7d866bd143371e629b01b7757fcfa1f0f58a360fa53' 
  AND token = 'oToFRyleXe9BiSvYAHBJVQdk1pn/3l6SVY0ocFo/tzw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}