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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67080edc8176184ffebbef26a55c50f1eec423c6289dc6408c7547b84078d2bb' 
  AND token = 'kfEkhweKJMeppcTln9Hs85SZkZG34P1h3rCryNzLQGE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}