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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51da9c659abaf196d65f58f70560160f0cf76848746c8e25a1566ed863ddab4c' 
  AND token = 'EVyfkpIlEbWVF+sZN1zpYyz0TBWxbaPe01ANLnpkVJo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}