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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33e5ef8559ca3709b9887daa3aa14c60ba44957c640b2a4bdd7e03b0a140d624' 
  AND token = 'XbT8s/gxpSs0ZAmWTyUZL/sIT5M+CA0+P5qcV9B6oB4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}