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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15aec3e7c491d82adec43e6865dfc7b81b6f5bc1f63bf62af6d4b70e055756a8' 
  AND token = 'O3Pnn3+nwwh01Dtr3O4ThO8+VyOSzOOo4Ld7LFidois=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}