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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04577a2b74982243c32717e47b452f665317d6eacd366cd3b2d1950b212495ee' 
  AND token = 'mDiOATJuBW+Ws+2+KS5c5s3rJHVAf2E0zDeXoPz8HVk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}