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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e4932e9d19d0fafbf8b671d2d4f5c2a7bc5e008a52d2fe59d67e270e131e95b' 
  AND token = 'C1/3Uhtx4i8ZpPoExWyapzrDKaRVUnuRGbDqo+37hW0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}