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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d3b279de3679389ab6628bd9c89a1287c2acff41c2fb2fa238231933ec489a3' 
  AND token = 'vDHn2+mFB9pX5k9XWw6A61ha2CFi7Z7eCBp4QcuLE9I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}