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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b77b004e4f7e8f994a561e8edb5c18e5af14828ff5fefe8b78fe2bbee62f414' 
  AND token = 'Cc6ttEK0wwfQHsUOIAB9sr88JXkzy+INxcfZYl7GDRA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}