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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca420efd744ed422b519a64285d124b67a98075da4eb1eac52c65320c2d7db0f' 
  AND token = 'FntIfhigLRL1lu0bVSV+JdkBf1AC0kJkf5iBMb5CcYA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}