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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae1a05bbe598c0a2345d4e834072b4db877434e2c6d0903e562450dc67dc5641' 
  AND token = 'YnuW0scD8b03OqCUuH++fsb69FFvCH6Zj2BhRae8onI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}