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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '577a4d23b50f1ec1640159aa1e1cba6d374058277bd232cb0aeec0bf08272278' 
  AND token = '7AbtgHe8LC8LZiSrH72THop99t63YT3EYkIs6NByCu0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}