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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dc894f9a1d97d137b861a5be6a08548ac191730e36c89e1cd369bf2e4aaa4107' 
  AND token = 'q+UQ2YmkJzuyWpESNjxCze1ySk+ginPVsoXgIy0Fkvs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}