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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8617a31211c91b1a7f4a9028c916925886a9024b04dae4bbe3315839a0b814f0' 
  AND token = 'ZFrU+aPdjXbRjyuoaA3qjb20YLLwD+p63W8SnfpP6ss=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}