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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf3154e3f22b2489d667b862a0f5cc3af2ad40b650a533bbdfc888836b651329' 
  AND token = '1YhF7NPOaDTVD77qO6oyuR2cI0b8XDUqyrljukb8NoQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}