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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eccaa810269f3ca0c9f93213b77ee5ea13dd257f14e53c254272be3b3e30bb8c' 
  AND token = 'AznXQWWBGCbI/Cvav+fy9vgfvubFVBSU+SeXECNyrr0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}