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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5e58a9603aa5d6f827867070c3ace681e7eda8ec324719a83b467981ae48d25' 
  AND token = 'C7gICkv2oEWs9hBzrLYvrOvVCCXaSNlkjxTeKX7SAvA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}