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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4954523e47df86782c6c8ea926a6509e0fa1cc24ed1b28d22f61cfe0de0c188a' 
  AND token = 's6Ev19AvQ2IOHNuChoQhjcmtPVMoEQ3kfod6EgP5/yM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}