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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2419f78b77f3125cdea5f4d7f8b2a4a5b40fb07ec019d30946db0f3daa7d3307' 
  AND token = 'pbiU9yhSuqmPlI7ih0PgJeuusCMkxlxYbwhS5zHoYD0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}