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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a146f920fb492124cf59d9bbbcf3a1c2abdf4517fd116c4c33b27d5e0ec1612' 
  AND token = 'C7gMfPBfQ30fQLQLAG10q3N+q2Ql0HbFsa0hl8ZMGQU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}