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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '527a9e41964ef4ceae205b1693e0dec5117d2dee2a3e94ebb15f1c2e971a5107' 
  AND token = 'fiMMQfcCu7xzd7Br4urJT8Fg0UPLkkqBlb53rB9diSM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}